Progenics And Cytogen Announce Progress On Vaccine And Antibody Therapies For Prostate Cancer

, Inc. and have announced new findings on immune therapies which may play a future role in the treatment of prostate and other cancers.

The therapies are directed against Prostate Specific Membrane Antigen (PSMA), a molecular cancer marker that is abundantly expressed on the surface of prostate cancer cells.

The developments, presented today at the 91st Annual Meeting of the American Association for Cancer Research (AACR), are the result of work being conducted under a joint venture between Progenics and Cytogen to develop prostate cancer immunotherapies based on PSMA.

Novel approaches for the creation and preclinical testing of therapeutic antibodies and vaccines to PSMA were reported by Gerald P. Donovan, Ph.D., Progenics’ Senior Staff Scientist, and Robert J. Israel, M.D., Progenics’ Vice President of Medical Affairs.

The therapeutic vaccine program includes recombinant PSMA protein immunogens as well as novel and proprietary viral vectors which deliver the PSMA gene to the immune system.

In animal studies, the vaccines have generated potent and specific immune responses to cell- surface PSMA.

The therapeutic antibody program includes both “naked” and radiolabelled monoclonal antibodies directed specifically to PSMA on the surface of prostate cancer cells.

“We have developed strategies for producing novel therapeutic antibodies as well as vaccines which elicit robust immune responses to PSMA,” said Dr. Donovan.

“These findings constitute an important step towards identifying the optimal therapeutic product candidates to advance into human clinical testing.” The PSMA gene was first identified by scientists at Memorial Sloan- Kettering Cancer Center in New York City.

PSMA was identified as a cell- surface protein that is abundantly expressed in prostate cancer cells and therefore is an attractive target for vaccine and antibody- based cancer immune therapies.

Further work demonstrated that PSMA is also present at high levels on newly formed blood vessels (neovasculature) needed for the growth and survival of many types of solid tumors.

These results indicate that PSMA- targeted therapies may have anti-angiogenesis effects and may prove valuable in treating a broad range of cancers.

“Through our joint venture with Cytogen and collaborations with leading academic researchers, we have been successful in rapidly advancing several promising product candidates into animal testing,” said Ronald J. Prentki, President of Progenics.

“This progress reflects our commitment to this exciting new technology, which we anticipate will lead to the first PSMA products entering human trials within the next twelve months.”

“By capitalizing on the unique characteristics of PSMA, we believe that our joint venture with Progenics can develop a range of new immunotherapies for prostate cancer,” said H. Joseph Reiser, Ph.D., Cytogen’s Chief Executive Officer.

“In addition, we intend to evaluate these therapies, as an anti- angiogenesis approach, in other cancers where PSMA is expressed.” Progenics Pharmaceuticals is a biopharmaceutical company focusing on the development and commercialization of products for the treatment and prevention of cancer, viral diseases, and neurological disorders.

Cytogen Corporation is an established biopharmaceutical company in Princeton, NJ, with two principal lines of business, proteomics and oncology.

Shopping Dragon Pharmaceutical Safely

Propionat 100 - Bulk Price
Propionat 100 - Bulk Price

Administration: Injection
Base Chemical Name: Testosterone Propionate
Produced by: Dragon Pharma Labs
Pack: 10 x 10 mL vial (100 mg/mL)
Price: 10 x $30.00

Dianabol 20 - Discount Price
Dianabol 20 - Discount Price

Administration: Oral
Base Ingredient: Methandrostenolone
Made by: Dragon Pharmaceutical
Unit: 30 x 100 tabs (20 mg/pill)
Price: 30 x $26.00

Trenbolone 200 - Cheap Price
Trenbolone 200 - Cheap Price

Administration: Injection
Active Chemical Name: Trenbolone Enanthate
Branded by: Dragon Pharma
Package: 20 x 10 mL vial (200 mg/mL)
Price: 20 x $67.00

Masteron 200 - Cheap Price
Masteron 200 - Cheap Price

Administration: Injection
Basic Ingredient: Drostanolone Enanthate
Branded by: Dragon Pharmaceutical
Pack: 20 x 10 mL vial (200 mg/mL)
Price: 20 x $60.00

NPP 150
NPP 150

Injectable Steroid for Muscle Growth
Prime Constituent: Nandrolone Phenylpropionate
Made by: Dragon Pharma Labs
10 mL Sterile Multi-dose Vial (150 mg/mL)

Propionat 100 [10 Vials]
Propionat 100 [10 Vials]

Injectable Steroid for Muscle Growth
Base Chemical Name: Testosterone Propionate
Producer: Dragon Pharmaceutical
10 Vials [10 mL per Vial (100 mg/ml)]
Price: 10 x $30.00 = $300.00 in Total

Dianabol
Dianabol

Oral Steroid for Muscle Growth
Prime Component: Methandrostenolone
Produced by: Dragon Pharma LLC
100 tabs (20 mg/tablet)

Parabolan 100
Parabolan 100

Principal Constituent: Trenbolone Hexahydrobenzylcarbonate
Producer: Dragon Pharma Labs
Package: 10 mL vial (100 mg/mL)

EQ 200 / Test E 200
EQ 200 / Test E 200

Main Ingredient: Boldenone Undecylenate, Testosterone Enanthate
Manufacturer: Dragon Pharmaceuticals
Pack: 10 mL vial (400 mg/mL)

Primobolan 100
Primobolan 100

Producer: Dragon Pharma Labs
Base Chemical Name: Methenolone Enanthate
Unit: 10 mL vial (100 mg/mL)

Winstrol Tabs Cheap Price
Winstrol Tabs Cheap Price

Branded by: Dragon Pharmaceuticals
Primary Substance: Stanozolol
Pack: 10 x 100 tabs (50 mg/tablet)
Package Price: 63.00 USD

Superdrol 10
Superdrol 10

Oral Anabolic Steroid
Prime Chemical Name: Methyldrostanolone
Manufacturer: Dragon Pharma LLC
Unit: 100 tablets (10 mg/tab)

TriTren 150 Best Price
TriTren 150 Best Price

Made by: Dragon Pharma LLC
Prime Substance: Tri Trenbolone
Unit: 30 x 10 mL vial (150 mg/mL)
Package Price: 59 USD

Propionat 100 Bulk Price
Propionat 100 Bulk Price

Produced by: Dragon Pharma LLC
Basal Constituent: Testosterone Propionate
Pack: 20 x 10 mL vial (100 mg/mL)
Package Price: 25.00 USD

Masteron 200 Best Price
Masteron 200 Best Price

Producer: Dragon Pharmaceutical
Active Component: Drostanolone Enanthate
Package: 30 x 10 mL vial (200 mg/mL)
Amount Price: 49.00 USD

Masteron 200 Cheap Priced
Masteron 200 Cheap Priced

Injectable Anabolic Steroid
Main Substance: Drostanolone Enanthate
Producer: Dragon Pharma LLC
Pack: 20 x 10 mL vial (200 mg/mL)
Price per Unit: 60.00 USD

Oxymetholon Cheap Price
Oxymetholon Cheap Price

Producer: Dragon Pharma
Prime Ingredient: Oxymetholone
Amount: 10 x 100 tablets (50 mg/pastille)
Amount Price: 65.00 USD

NPP 150 Cheap Price
NPP 150 Cheap Price

Made by: Dragon Pharma LLC
Principal Substance: Nandrolone Phenylpropionate
Package: 10 x 10 mL vial (150 mg/mL)
Package Price: 30.00 USD

Masteron 100 for Sale
Masteron 100 for Sale

Injectable Anabolic Steroid
Base Constituent: Drostanolone Di-Propionate
Made by: Dragon Pharma
Package: 10 x 10 mL vial (100 mg/mL)
Price per Package: 49.00 USD

Oxymetholon Bulk Price
Oxymetholon Bulk Price

Manufacturer: Dragon Pharmaceutical
Active Component: Oxymetholone
Amount: 20 x 100 tablets (50 mg/tab)
Pack Price: 57.00 USD

Cut Long 300
Cut Long 300

Producer: Dragon Pharma LLC
Active Chemical Name: Drostanolone Enanthate, Testosterone Enanthate, Trenbolone Enanthate
Unit: 10 mL vial (300 mg/mL)

Cypionat 250 Cheap Price
Cypionat 250 Cheap Price

Branded by: Dragon Pharma Labs
Active Substance: Testosterone Cypionate
Pack: 10 x 10 mL vial (250 mg/mL)
Amount Price: 36.00 USD

Clomid for Sale
Clomid for Sale

Post Cycle Therapy Anabolic Steroid
Basic Substance: Clomiphene Citrate
Branded by: Dragon Pharma
Package: 10 x 100 tabs (50 mg/pill)
Price per Amount: 63.00 USD

Clenbuterol Cheap Price
Clenbuterol Cheap Price

Branded by: Dragon Pharma
Primary Component: Clenbuterol Hydrochloride
Unit: 10 x 100 tablets (40 mcg/pill)
Package Price: 25.00 USD

EQ 500
EQ 500

Produced by: Dragon Pharma Labs
Base Substance: Boldenone Undecylenate
Package: 10 mL vial (500 mg/mL)

Oxymetholon Best Price
Oxymetholon Best Price

Made by: Dragon Pharma Labs
Prime Substance: Oxymetholone
Amount: 30 x 100 pills (50 mg/pastille)
Amount Price: 51.00 USD

EQ 300
EQ 300

Produced by: Dragon Pharma Labs
Primary Constituent: Boldenone Undecylenate
Package: 10 mL vial (300 mg/mL)

Oxymetholon Low Priced
Oxymetholon Low Priced

Oral Anabolic Steroid
Basal Component: Oxymetholone
Produced by: Dragon Pharma Labs
Unit: 30 x 100 tablets (50 mg/tablet)
Price per Unit: 51.00 USD

Winstrol
Winstrol

Primary Ingredient: Stanozolol
Produced by: Dragon Pharma
Package: 100 tabs (50 mg/tablet)

EQ 200 / Test E 200
EQ 200 / Test E 200

Basal Constituent: Boldenone Undecylenate, Testosterone Enanthate
Producer: Dragon Pharmaceuticals
Unit: 10 mL vial (400 mg/mL)

Proviron
Proviron

Androgenic Steroidal Agent
Main Ingredient: Mesterolone
Manufacturer: Dragon Pharma Labs
Pack: 100 pastilles (20 mg/tab)

Dianabol 20
Dianabol 20

Oral Anabolic Steroid
Prime Component: Methandrostenolone
Manufacturer: Dragon Pharma LLC
Amount: 100 pastilles (20 mg/pill)

Trenbolone 100
Trenbolone 100

Manufacturer: Dragon Pharma Labs
Primary Component: Trenbolone Acetate
Package: 10ml vial (100 mg/ml)

Propionat 100 Best Price
Propionat 100 Best Price

Manufacturer: Dragon Pharma LLC
Main Chemical Name: Testosterone Propionate
Pack: 30 x 10 mL vial (100 mg/mL)
Pack Price: 20.00 USD

Parabolan 100
Parabolan 100

Basal Component: Trenbolone Hexahydrobenzylcarbonate
Made by: Dragon Pharma
Pack: 10 ml vial (100 mg/ml)

Winstrol Tabs Bulk Price
Winstrol Tabs Bulk Price

Made by: Dragon Pharmaceuticals
Active Chemical Name: Stanozolol
Amount: 20 x 100 tablets (50 mg/tablet)
Package Price: 58.00 USD