Microcide Pharmaceuticals, Inc. has entered into a research collaborative agreement with Discovery Partners International, Inc., to optimise the drug-like qualities of Microcide’s recently discovered broad-spectrum antifungal compound series.
Using Microcide’s proprietary microbial genomics VALID System, the Company has discovered and developed a series of promising antifungal compounds to the point of lead optimisation.
Members of the series have a defined, selective mechanism-of-action, and a broad- spectrum of activity against key fungal pathogens.
In order to accelerate the lead optimisation process, Microcide has chosen to collaborate with Discovery Partners, which is highly skilled in the preparation of chemical libraries by parallel synthesis, using both solid- and solution-phase methods.
The compounds that advance from this lead optimisation effort into preclinical development will be targeted for treatment of serious systemic fungal infections, including documented or suspected Candida and Aspergillus infections.
“We are very pleased to be working with Discovery Partners at this stage in our antifungal product development efforts.
They have proprietary capabilities relating to combinatorial chemistry and the synthesis of compounds which will allow us to optimise our attractive lead series at a faster pace,” said Jim Rurka, President & CEO of Microcide.
Microcide is a biopharmaceutical company committed to the discovery, development and commercialisation of novel antimicrobials for the improved treatment of serious bacterial, fungal and viral infections.
The Company’s three discovery research platforms address the growing problems of antibiotic resistance and the need for improved antifungal and antiviral therapeutics.
Shop Dragon Pharma Steroids
Discount pharmacy seller of Dragon Pharma: Order Dianabol 20mg.
Best Dragon Pharma Steroids
Discount pharmacy supplier of Dragon Pharma: Buy Where to buy anabolic steroids online safely? On-Line.