Schering, Philogen Agree License Deal

Schering AG, and S.r.l., have announced that Schering acquired exclusive worldwide development and marketing rights for an antibody-based therapeutic fusion protein from Philogen. It is expected to have the potential to treat solid tumors by triggering immunological mechanisms.

Financial details were not disclosed.

“We consider antibodies to have the potential for outstanding efficacy in oncology. We believe that the Philogen fusion protein technology has true breakthrough potential product features which would really take tumor treatment to a new level of benefit for the patients,” said Dr Joachim-Friedrich Kapp, Head of Specialized Therapeutics at Schering Grou.

“We are convinced that we could deliver new hope to physicians and cancer patients, if this innovative antibody treatment confirms the promising preclinical results obtained so far,” said Dr. Duccio Neri of Philogen.

The antibody-based compound consists of a fusion protein with anti-tumor activity, which binds to an angiogenesis associated antigen expressed by a broad spectrum of solid tumors.

This antigen is one of the few good quality markers of pathological neo-angiogenesis known so far. In 1999, Schering and Philogen started their cooperation on the antibody compound, when Schering acquired an exclusive imaging license from Philogen and got an option for an exclusive therapeutic license.

Philogen is a leading Italian biotech company founded in 1996 by the brothers Duccio, Giovanni and Dario Neri, and Dr. Luciano Zardi.

Dario Neri is a Professor of Biomacromolecules at the Swiss Federal Insitute of Technology, Zurich.

Prof. Luciano Zardi is the Director of the Laboratories of Cell Biology of the National Institute of Cancer Research in Genoa, Italy.

Schering AG is a research-based pharmaceutical company.

Its activities are focused on four business areas: Fertility Control&Hormone Therapy, Diagnostics&Radiopharmaceuticals, Dermatology as well as Specialized Therapeutics for disabling diseases in the fields of the central nervous system, oncology and cardiovascular system.

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